Engineering of Halogenases towards Synthetic Applications - Increasing the Thermostability and Investigations on a Marine Brominase Bmp5

di Hannah Minges
Stato: Nuovo
67,99 €
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Hannah Minges Engineering of Halogenases towards Synthetic Applications - Increasing the Thermostability and Investigations on a Marine Brominase Bmp5
Hannah Minges - Engineering of Halogenases towards Synthetic Applications - Increasing the Thermostability and Investigations on a Marine Brominase Bmp5

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Descrizione

Hannah Minges focuses on the investigation of two different FAD-dependent halogenases in order to analyze and improve their applicability for chemoenzymatic approaches in chemistry. Owing to beneficial features, like high selectivity and benign reaction conditions, nature’s toolkit for halogenation provides several advantages, whereas conventional chemical strategies require hazardous reagents and suffer from low selectivity. Therefore, enzymatic halogenation arises as promising alternative in the synthesis of valuable chemicals. One project focuses on the generation of a thermostable variant of the tryptophan halogenase Thal by means of directed evolution. The second project deals with the investigation of the marine halogenase Bmp5. This enzyme is of synthetic interest because it preferably introduces bromine into phenol compounds, whereas chlorination cannot take place.

Contributori

Scrittore:
Hannah Minges

Ulteriori informazioni

Illustrations Note:
XII, 116 p. 46 illus., 9 illus. in color.
Indice:

Halogenating Enzymes.- Identification of a Thermostable Thal Variant by Directed Evolution.- Establishment of the Brominase Bmp5 for Synthetic Application.

Commenti:
Evolution and investigations on halogenases


Includes supplementary material: sn.pub/extras

Tipo multimediale:
Copertina morbida
Editore:
Springer Fachmedien Wiesbaden GmbH
Biografia:
Hannah Minges, a Ph.D student at Bielefeld University, works on the optimization of tryptophan halogenases by means of directed evolution.
Lingua:
Inglese
Edizione:
1st ed. 2017
Numero di Pagine:
116

Dati Principali

Tipologia prodotto:
Brossura
Data di pubblicazione:
23 maggio 2017
Dimensioni del collo:
0.21 x 0.148 x 0.007 m; 0.178 kg
GTIN:
09783658184094
DUIN:
VPIMT9CNKOE
67,99 €
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