Epigenetic Analysis of Human Embryonic Stem Cells

di Chávez, Lukas
Stato: Nuovo
76,83 €
IVA inclusa - Spedizione GRATUITA
Chávez, Lukas Epigenetic Analysis of Human Embryonic Stem Cells
Chávez, Lukas - Epigenetic Analysis of Human Embryonic Stem Cells

Ti piace questo prodotto? Condividilo con i tuoi amici!

76,83 € IVA inclusa
Solo 1 articolo rimasto Solo 1 articoli rimasti Più di 10 pezzi disponibili
Consegna: tra lunedì 18 luglio 2022 e mercoledì 20 luglio 2022
Vendita & spedizione: Dodax

Descrizione

Human embryonic stem cells (hESCs) hold promise for future cell replacement therapy because they can be induced to differentiate into a wide variety of cell types. DNA methylation is a crucial epigenetic mechanism involved in normal cellular differentiation. The author Lukas Chavez introduces into several experimental and computational methods commonly applied for the analysis of genetic and epigenetic characteristics. Subsequently, he develops and comprehensively describes computational methods for the analysis of novel genome-wide DNA methylation data. In a case study, the computational methods are applied to DNA methylation data derived from hESCs. The author analyzes the interplay between DNA methylation, histone modifications, and transcription factor binding, and investigates the effect of differential methylation on gene expression. The results given in this book extend our knowledge of interactions between genetic and epigenetic mechanisms during early differentiation of hESCs. The book is of most interest not only for stem cell biologists but also for researchers interested in computational methods available for high-throughput studies in health and disease.

Contributori

Scrittore:
Chávez, Lukas

Ulteriori informazioni

Biografia:
Lukas Chávez obtained his PhD in Computational Biology at the Max-Planck-Institute for Molecular Genetics and Freie Universität Berlin. Currently, he works as a PostDoc at the Max-Planck-Institute for Molecular Genetics where he analyzes epigenetic modifications during cancer development.
Lingua:
Inglese
Numero di Pagine:
140
Tipo multimediale:
Copertina morbida
Editore:
Südwestdeutscher Verlag für Hochschulschriften

Dati Principali

Tipologia prodotto:
Brossura
Dimensioni del collo:
0.22 x 0.15 x 0.008 m; 0.254 kg
GTIN:
09783838127620
DUIN:
LLRB2KR932F
76,83 €
Utilizziamo i cookie sul nostro sito Web per rendere la tua visita più efficiente e più user-friendly. Per assicurarti di poter utilizzare tutte le funzioni presenti, fai clic su "accetta cookie". Per ulteriori informazioni, consulta la nostra Informativa sulla privacy.