Epigenetic Analysis of Human Embryonic Stem Cells

di Chávez, Lukas
Stato: Nuovo
76,83 €
IVA inclusa - Spedizione GRATUITA
Chávez, Lukas Epigenetic Analysis of Human Embryonic Stem Cells
Chávez, Lukas - Epigenetic Analysis of Human Embryonic Stem Cells

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76,83 € IVA inclusa
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Consegna: tra lunedì 18 luglio 2022 e mercoledì 20 luglio 2022
Vendita & spedizione: Dodax


Human embryonic stem cells (hESCs) hold promise for future cell replacement therapy because they can be induced to differentiate into a wide variety of cell types. DNA methylation is a crucial epigenetic mechanism involved in normal cellular differentiation. The author Lukas Chavez introduces into several experimental and computational methods commonly applied for the analysis of genetic and epigenetic characteristics. Subsequently, he develops and comprehensively describes computational methods for the analysis of novel genome-wide DNA methylation data. In a case study, the computational methods are applied to DNA methylation data derived from hESCs. The author analyzes the interplay between DNA methylation, histone modifications, and transcription factor binding, and investigates the effect of differential methylation on gene expression. The results given in this book extend our knowledge of interactions between genetic and epigenetic mechanisms during early differentiation of hESCs. The book is of most interest not only for stem cell biologists but also for researchers interested in computational methods available for high-throughput studies in health and disease.


Chávez, Lukas

Ulteriori informazioni

Lukas Chávez obtained his PhD in Computational Biology at the Max-Planck-Institute for Molecular Genetics and Freie Universität Berlin. Currently, he works as a PostDoc at the Max-Planck-Institute for Molecular Genetics where he analyzes epigenetic modifications during cancer development.
Numero di Pagine:
Tipo multimediale:
Copertina morbida
Südwestdeutscher Verlag für Hochschulschriften

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Tipologia prodotto:
Dimensioni del collo:
0.22 x 0.15 x 0.008 m; 0.254 kg
76,83 €
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