Endocannabinoid Regulation of Monoamines in Psychiatric and Neurological Disorders
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Endocannabinoids and monoamines: modulating the modulators.- Endocannabinoid-mediated synaptic plasticity.- Current cannabinoid receptor nomenclature and pharmacological principles.- Cue-elicited craving for cannabis activates the reward neurocircuitry associated with the neuropathology of addiction.- Cannabinoid modulation of dopaminergic circuits in neurodegenerative and neuropsychiatric disorders.- Pathophysiology of mood disorders and mechanisms of action of antidepressants and mood stabilizers.- Anatomical, biochemical and behavioral evidence for cannabinoid modulation of noradrenergic circuits: role of norepinephrine in cannabinoid-induced aversion.- Gender Disparity of Depression: The Role of Endocannabinoids and Noradrenergic Function.- Endocannabinoids, Monoamines and Stress.- Chronic effects of cannabinoid drugs on monoaminergic systems and the role of endocannabinoids and cannabinoid receptors in human brain disorders.- Endocannabinoid Signaling and the Regulation of the Serotonin System.- Modulation of serotonin firing activity through CB1 agonists and FAAH inhibitors.- Involvement of serotonergic system in cannabinoid analgesia.- Cannabinoids, monoamines, COMT and schizophrenia: pathobiological mechanisms in psychosis.
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From the reviews:"This book reviews the expansion of our understanding of cannabinoid modulation of monoaminergic circuits and their interactions in a variety of psychiatric and neurological disorders. ... intended for readers familiar with both clinical and preclinical research in this area, including individuals at all research, educational, and clinical levels interested in issues related to the use of cannabinoids for medical purposes. ... a detailed and technical review of recent information on this receptor system and how it relates to a number of neurological and psychiatric disorders." (Michael Easton, Doody's Book Reviews, February, 2014)